- Generation of heart and vascular system in rodents by blastocyst complementation. Coppiello G, Barlabé P, Moya-Jódar M, Abizanda G, Pogontke C, Barreda C, Iglesias E, Linares J, Arellano-Viera E, Larequi E, San Martín-Úriz P, Carvajal-Vergara X, Pelacho B, Mazo MM, Pérez-Pomares JM, Ruiz-Villalba A, Ullate-Agote A, Prósper F, Aranguren XL. Dev Cell. 2023; S1534-5807(23)00552-X. doi: 10.1016/j.devcel.2023.10.008. PMID: 37967560.
- Origin of congenital coronary arterio-ventricular fistulae from anomalous epicardial and myocardial development. Palmquist-Gomes P, Ruiz-Villalba A, Guadix JA, Romero JP, Bessiéres B, MacGrogan D, Conejo L, Ortiz A, Picazo B, Houyel L, Gómez-Cabrero D, Meilhac SM, de la Pompa JL, Pérez-Pomares JM. Exp Mol Med. 2023; 55:228-239. doi: 10.1038/s12276-022-00913-x. PMID: 36653444.
- A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Siguero-Álvarez M, Salguero-Jiménez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sánchez-Sáez F, Piñeiro-Sabarís R, Felipe-Medina N, Torroja C, Gómez MJ, Sabater-Molina M, Escribá R, Richaud-Patin I, Iglesias-García O, Sbroggio M, Callejas S, O’Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibañez B, Monserrat L, Pérez-Pomares JM, Sánchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL. Circulation. 2023; 147:47-65. doi: 10.1161/CIRCULATIONAHA.121.058767. PMID: 36325906.
- Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation. Carmona R, López-Sánchez C, Garcia-Martinez V, Garcia-López V, Muñoz-Chápuli R, Lozano-Velasco E, Franco D. J Cardiovasc Dev Dis. 2023; 10:440. doi: 10.3390/jcdd10110440.
- Cardiomyocyte-Specific Wt1 Is Involved in Cardiac Metabolism and Response to Damage. Díaz Del Moral S, Benaouicha M, Villa Del Campo C, Torres M, Wagner N, Wagner KD, Muñoz-Chápuli R, Carmona R. J Cardiovasc Dev Dis. 2023; 10:211. doi: 10.3390/jcdd10050211.
- Development of an injectable alginate-collagen hydrogel for cardiac delivery of extracellular vesicles. Gil-Cabrerizo P, Saludas L, Prósper F, Abizanda G, Echanove-González de Anleo M, Ruiz-Villalba A, Garbayo E, Blanco-Prieto MJ. Int J Pharm. 2022; 629:122356. doi: 10.1016/j.ijpharm.2022.122356. PMID: 36332831.
- Dynamic Epicardial Contribution to Cardiac Interstitial c-Kit and Sca1 Cellular Fractions. Pogontke C, Guadix JA, Sánchez-Tévar AM, Muñoz-Chápuli R, Ruiz-Villalba A, Pérez-Pomares JM. Front Cell Dev Biol. 2022; 10:864765. doi: 10.3389/fcell.2022.864765. PMID: 35706902.
- In Vivo and In Vitro Cartilage Differentiation from Embryonic Epicardial Progenitor Cells. Palmquist-Gomes P, Marín-Sedeño E, Ruiz-Villalba A, Rico-Llanos GA, Pérez-Pomares JM, Guadix JA. Int J Mol Sci. 2022; 23:3614. doi: 10.3390/ijms23073614. PMID: 35408974.
- A New Versatile Platform for Assessment of Improved Cardiac Performance in Human-Engineered Heart Tissues. Ribeiro MC, Rivera-Arbeláez JM, Cofiño-Fabres C, Schwach V, Slaats RH, Ten Den SA, Vermeul K, van den Berg A, Pérez-Pomares JM, Segerink LI, Guadix JA, Passier R. J Pers Med. 2022; 12:214. doi: 10.3390/jpm12020214. PMID: 35207702.
- Isolation methods of large and small extracellular vesicles derived from cardiovascular progenitors: A comparative study. Saludas L, Garbayo E, Ruiz-Villalba A, Hernández S, Vader P, Prósper F, Blanco-Prieto MJ. Eur J Pharm Biopharm. 2022; 170:187-196. doi: 10.1016/j.ejpb.2021.12.012. PMID: 34968647.
- Cq Values Do Not Reflect Nucleic Acid Quantity in Biological Samples. Ruijter JM, Ruiz-Villalba A, van den Hoff MJB. Clin Chem. 2021; 68:7-9. doi: 10.1093/clinchem/hvab236. PMID: 34677605
- Training biochemistry students in experimental developmental biology: Induction of cardia bifida formation in the chick embryo. Palmquist-Gomes P, Pérez-Pomares JM, Guadix JA. Biochem Mol Biol Educ. 2021; 49:782-788. doi: 10.1002/bmb.21549. PMID: 34156745.
- Sporulation is dispensable for the vegetable-associated life cycle of the human pathogen Bacillus cereus. Antequera-Gómez ML, Díaz-Martínez L, Guadix JA, Sánchez-Tévar AM, Sopeña-Torres S, Hierrezuelo J, Doan HK, Leveau JHJ, de Vicente A, Romero D. Microb Biotechnol. 2021; 14:1550-1565. doi: 10.1111/1751-7915.13816. PMID: 33955675.
- Use and Misuse of Cq in qPCR Data Analysis and Reporting. Ruiz-Villalba A, Ruijter JM, van den Hoff MJB. Life (Basel). 2021; 11:496. doi: 10.3390/life11060496. PMID: 34072308.
- Understanding the Adult Mammalian Heart at Single-Cell RNA-Seq Resolution. Marín-Sedeño E, de Morentin XM, Pérez-Pomares JM, Gómez-Cabrero D, Ruiz-Villalba A. Front Cell Dev Biol. 2021; 9:645276. doi: 10.3389/fcell.2021.645276. PMID: 34055776.
- Delivery of cardiovascular progenitors with biomimetic microcarriers reduces adverse ventricular remodeling in a rat model of chronic myocardial infarction. Garbayo E, Ruiz-Villalba A, Hernandez SC, Saludas L, Abizanda G, Pelacho B, Roncal C, Sanchez B, Palacios I, Prósper F, Blanco-Prieto MJ. Acta Biomater. 2021; 126:394-407. doi: 10.1016/j.actbio.2021.03.017. PMID: 33716175.
- Extracellular Vesicle-Based Therapeutics for Heart Repair. Saludas L, Oliveira CC, Roncal C, Ruiz-Villalba A, Prósper F, Garbayo E, Blanco-Prieto MJ. Nanomaterials (Basel). 2021; 11:570. doi: 10.3390/nano11030570. PMID: 33668836.
- Fsp1 cardiac embryonic expression delineates atrioventricular endocardial cushion, coronary venous and lymphatic valve development. Cano-Ballesteros S, Palmquist-Gomes P, Marín-Sedeño E, Guadix JA, Pérez-Pomares JM. J Anat. 2021; 238:508-514. doi: 10.1111/joa.13306. PMID: 32920869.
- The Insulin-like Growth Factor Signalling Pathway in Cardiac Development and Regeneration. Díaz Del Moral S, Benaouicha M, Muñoz-Chápuli R, Carmona R. Int J Mol Sci. 2021; 23:234. doi: 10.3390/ijms23010234.
- GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells. Arroyo N, Villamayor L, Díaz I, Carmona R, Ramos-Rodríguez M, Muñoz-Chápuli R, Pasquali L, Toscano MG, Martín F, Cano DA, Rojas A. JCI Insight. 2021; 6:e150059. doi: 10.1172/jci.insight.150059.
- Deletion of the Wilms’ Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Díaz Del Moral S, Barrena S, Hernández-Torres F, Aránega A, Villaescusa JM, Gómez Doblas JJ, Franco D, Jiménez-Navarro M, Muñoz-Chápuli R, Carmona R. Front Cell Dev Biol. 2021; 9:683861. doi: 10.3389/fcell.2021.683861.
- Bone marrow contribution to the heart from development to adulthood. Sampaio-Pinto V, Ruiz-Villalba A, Nascimento DS, Pérez-Pomares JM. Semin Cell Dev Biol. 2021; 112:16-26. doi: 10.1016/j.semcdb.2020.06.008. PMID: 32591270.
- Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial Infarction. Ruiz-Villalba A, Romero JP, Hernández SC, Vilas-Zornoza A, Fortelny N, Castro-Labrador L, San Martin-Uriz P, Lorenzo-Vivas E, García-Olloqui P, Palacio M, Gavira JJ, Bastarrika G, Janssens S, Wu M, Iglesias E, Abizanda G, de Morentin XM, Lasaga M, Planell N, Bock C, Alignani D, Medal G, Prudovsky I, Jin YR, Ryzhov S, Yin H, Pelacho B, Gomez-Cabrero D, Lindner V, Lara-Astiaso D, Prósper F. Circulation. 2020; 142:1831-1847. doi: 10.1161/CIRCULATIONAHA.119.044557. PMID: 32972203.
- Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice. Rivaud MR, Marchal GA, Wolswinkel R, Jansen JA, van der Made I, Beekman L, Ruiz-Villalba A, Baartscheer A, Rajamani S, Belardinelli L, van Veen TAB, Basso C, Thiene G, Creemers EE, Bezzina CR, Remme CA. Europace. 2020; 22:1579-1589. doi: 10.1093/europace/euaa127. PMID: 32778883.
- An overview of international regulatory frameworks for mesenchymal stromal cell-based medicinal products: From laboratory to patient. López-Beas J, Guadix JA, Clares B, Soriano-Ruiz JL, Zugaza JL, Gálvez-Martín P. Med Res Rev. 2020; 40:1315-1334. doi: 10.1002/med.21659. PMID: 32017179.
- Indolenine-Based Derivatives as Customizable Two-Photon Fluorescent Probes for pH Bioimaging in Living Cells. Benitez-Martin C, Guadix JA, Pearson JR, Najera F, Perez-Pomares JM, Perez-Inestrosa E. ACS Sens. 2020; 5:1068-1074. doi: 10.1021/acssensors.9b02590. PMID: 32227860.
- Two genomic regions encoding exopolysaccharide production systems have complementary functions in B. cereus multicellularity and host interaction. Caro-Astorga J, Álvarez-Mena A, Hierrezuelo J, Guadix JA, Heredia-Ponce Z, Arboleda-Estudillo Y, González-Munoz E, de Vicente A, Romero D. Sci Rep. 2020; 10:1000. doi: 10.1038/s41598-020-57970-3. PMID: 31969664.
- Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors. García-Olloqui P, Rodriguez-Madoz JR, Di Scala M, Abizanda G, Vales Á, Olagüe C, Iglesias-García O, Larequi E, Aguado-Alvaro LP, Ruiz-Villalba A, Prosper F, Gonzalez-Aseguinolaza G, Pelacho B. J Tissue Eng Regen Med. 2020; 14:123-134. doi: 10.1002/term.2974. PMID: 31677236.
- Embryonic circulating endothelial progenitor cells. Díaz Del Moral S, Barrena S, Muñoz-Chápuli R, Carmona R. Angiogenesis. 2020; 23:531-541. doi: 10.1007/s10456-020-09732-y.
- Contribution of a GATA4-Expressing Hematopoietic Progenitor Lineage to the Adult Mouse Endothelium. Carmona R, Moral SDD, Barrena S, Muñoz-Chápuli R. Cells. 2020; 9:1257. doi: 10.3390/cells9051257.
- Epicardial cell lineages and the origin of the coronary endothelium. Carmona R, Barrena S, López Gambero AJ, Rojas A, Muñoz-Chápuli R. FASEB J. 2020; 34:5223-5239. doi: 10.1096/fj.201902249RR.
- Removal of artifact bias from qPCR results using DNA melting curve analysis. Ruijter JM, Ruiz-Villalba A, van den Hoff AJJ, Gunst QD, Wittwer CT, van den Hoff MJB. FASEB J. 2019; 33:14542-14555. doi: 10.1096/fj.201901604R. PMID: 31682470.
- Principal Criteria for Evaluating the Quality, Safety and Efficacy of hMSC-Based Products in Clinical Practice: Current Approaches and Challenges. Guadix JA, López-Beas J, Clares B, Soriano-Ruiz JL, Zugaza JL, Gálvez-Martín P. Pharmaceutics. 2019; 11:552. doi: 10.3390/pharmaceutics11110552. PMID: 31652984.
- Platinum-Doped Dendritic Structure as a Phosphorescent Label for Bacteria in Two-Photon Excitation Microscopy. Molina N, Cnudde M, Guadix JA, Perez-Pomares JM, Strassert CA, Vida Y, Perez-Inestrosa E. ACS Omega. 2019; 4:13027-13033. doi: 10.1021/acsomega.9b00639. PMID: 31460429.
- Synthesis of Amino Terminal Clicked Dendrimers. Approaches to the Application as a Biomarker. Molina N, Nájera F, Guadix JA, Perez-Pomares JM, Vida Y, Perez-Inestrosa E. J Org Chem. 2019; 84:10197-10208. doi: 10.1021/acs.joc.9b01369. PMID: 31310119.
- Cellular identities in an unusual presentation of cyclopia in a chick embryo. Palmquist-Gomes P, Pérez-Pomares JM, Guadix JA. J Exp Zool B Mol Dev Evol. 2019; 332:179-186. doi: 10.1002/jez.b.22893. PMID: 31298492.
- Mesothelial-mesenchymal transitions in embryogenesis. Carmona R, Ariza L, Cano E, Jiménez-Navarro M, Muñoz-Chápuli R. Semin Cell Dev Biol. 2019; 92:37-44. doi: 10.1016/j.semcdb.2018.09.006. PMID: 30243860.
- Cell-based therapies for the treatment of myocardial infarction: lessons from cardiac regeneration and repair mechanisms in non-human vertebrates. Palmquist-Gomes P, Pérez-Pomares JM, Guadix JA. Heart Fail Rev. 2019; 24:133-142. doi: 10.1007/s10741-018-9750-8. PMID: 30421074.
- Retinoids in Stellate Cells: Development, Repair, and Regeneration. Carmona R, Barrena S, Muñoz-Chápuli R. J Dev Biol. 2019; 7:10. doi: 10.3390/jdb7020010
- The Wilms’ tumor suppressor gene regulates pancreas homeostasis and repair. Ariza L, Rojas A, Muñoz-Chápuli R, Carmona R. PLoS Genet. 2019; 15:e1007971. doi: 10.1371/journal.pgen.1007971.
- Development of the Myocardial Interstitium. Pogontke C, Guadix JA, Ruiz-Villalba A, Pérez-Pomares JM. Anat Rec (Hoboken). 2019; 302:58-68. doi: 10.1002/ar.23915. PMID: 30288955.
• Ernesto Marín Sedeño. Epicardial development revisited: proepicardial heterogeneity. 2024. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. José María Pérez Pomares, Dr. Adrian Ruiz Villalba.
• Sandra Díaz del Moral. Functions of the Wilms´tumor suppressor gene (Wt1) in embryonic and adult myocardium. 2023. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. Ramón Muñoz-Chápuli Oriol, Dr. Rita Carmona Mejías.
• Cláudia Patrícia da Costa Oliveira. Secretome of epicardial-derived cells: extracelular vesicles and matrix. 2021. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. José María Pérez Pomares, Dr. Adrian Ruiz Villalba.
• Cristina Pogontke Díaz. Pericoronary cell response to cardiac damage: blood-borne cells and neurovascular interactions. 2021. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. José María Pérez Pomares, Dr. Juan Antonio Guadix Domínguez.
• Sara Cano Ballesteros. FSP1/S100A4 delineates distinct cardiac cell populations. 2020. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. José María Pérez Pomares, Dr. Juan Antonio Guadix Domínguez.
• Paul Palmquist Gomes. Developmental bases of cardiac vascularization and regeneration. 2019. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisors: Prof. José María Pérez Pomares, Dr. Juan Antonio Guadix Domínguez.
• Laura María Ariza Medina. El gen supresor del tumor de Wilms (Wt1) en el desarrollo, homeostasis y regeneración del páncreas. 2019. Sobresaliente Cum Laude. Supervisors: Prof. Ramón Muñoz-Chápuli Oriol, Dr. Rita Carmona Mejías.
• Adrián Ruiz Villaba. Origen y diversidad del intersticio cardiaco. 2014. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisor: Prof. José María Pérez Pomares.
• Elena Cano Rincón. Studies on the coelomic epithelium: novel development roles and mechanisms of repair. 2013. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisor: Prof. Ramón Muñoz-Chápuli Oriol.
• Álvaro Köhn Luque. Modelos matemáticos de desarrollo vascular. 2012. Sobresaliente Cum Laude con mención Doctorado Internacional. Supervisor: Prof. Miguel Ángel Herrero García, Prof. José María Pérez Pomares.
• Juan Antonio Guadix Domínguez. Estudio de las funciones del gen supresor del tumor de Wilms (Wt1) durante la diferenciación de los derivados epicárdicos embrionarios. 2010. Sobresaliente Cum Laude con mención Doctorado Europeus. Premio extraordinario de doctorado. Supervisors: Prof. Ramón Muñoz-Chápuli Oriol, Prof. José María Pérez Pomares.
• Rita Carmona Mejías. Origen y diferenciación de las células derivadas del epitelio celómico esplancnopleural en embriones de ave y mamífero. 2002. Sobresaliente Cum Laude. Premio extraordinario de doctorado. Supervisor: Prof. Ramón Muñoz-Chápuli Oriol.
